![]() Ammonium levels were significantly decreased during the final week of treatment (TC, P = 0.02 DC, P = 0.03). Propionate levels increased significantly in the TC (week 2, P = 0.02 week 3, P = 0.0019) and DC (week 2, P = 0.03) with treatment while lactate levels significantly decreased in the TC (week 3, P = 0.03). Changes in microbial community activity and composition between the control and treatment periods were evaluated for each colon compartment (ascending, transverse, and descending colon ). Following a stabilization period and a control period (2 weeks each), the reactor feed was supplemented with daily MegaSporeBiotic™ for 3 weeks (treatment period). The effects of MegaSporeBiotic™ on gut microbiota activity and community composition were evaluated for the first time using an in vitro model of the human gastrointestinal tract, the simulator of the human intestinal microbial ecosystem (SHIME®), under healthy conditions. (Bacillus indicus HU36, Bacillus subtilis HU58, Bacillus coagulans SC208, Bacillus licheniformis S元07, and Bacillus clausii SC109). ![]() Shop for Microbiome Labs Mega SporeBiotic from NHC, and experience the difference its 5 probiotic strains make to your health and wellness for yourself.MegaSporeBiotic™ is an oral, spore-based probiotic comprised of five Bacillus spp. Try this trusted probiotic supplement with food. The formula has been carefully vetted and approved for quality by our certified natural healthcare practitioners. Mega SporeBiotic from Microbiome Labs provides shelf-stable support for gut health and healthy immune function. The Food and Drug Administration (FDA) recommends consulting with your healthcare practitioner before giving supplements to children under 5 years old. (3) A healthy microbiome features balanced levels of microorganisms (about 300 to 500 different species of bacteria) living naturally in your intestines and digestive system, which help your body's internal immune response, weight management, and normal digestion. The gut is where the immune system starts, so maintaining a healthy gut also promotes healthy immune function. Probiotics help support gut health and overall wellness by promoting a healthy gut microbiome.
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